The boundaries between psychotic experiences, artistic production, and mystical states of consciousness remain a contested topic in psychology and psychiatry. Modern cognitive and neurobiological models, as well as psychoanalytic and existential explanations, largely overlook distinctions emphasized in classical Islamic psychology (Ilm al-Nafs). These include the foundational instinctual forces, the hierarchical functioning of cognitive structures, and the notion that the center of decision-making and values is not limited to the mind alone, but also involves the heart, conscience, and spiritual layers of consciousness. This paper aims to explore the conceptual contributions that Ilm al-Nafs can offer in understanding the phenomenological differences between psychotic fragmentation, artistic creation, and mystical experience. This study is based on the synthesis of four main sources: 1) Clinical observations: Insights into cognitive fragmentation, thought-action fusion, and the loss of symbolic capacity observed in chronic psychotic patients. 2) Comparative analysis: Examination of psychoanalytic, existential, cognitive, and Ilm al-Nafs perspectives and their explanatory models. 3) Islamic intellectual tradition: Discussions on the distinctions between madness and wisdom within classical Islamic thought. 4) Theoretical implications: Exploration of symbolic-level differences among psychotic, artistic, and religious productions, and the underlying mechanisms that account for these variations. The findings can be summarized as follows: 1) Psychosis: Impulsive energies (kuvve-i shahawiyya and gadabiyya) bypass the filter of reason and reach the decision-making mechanism directly; images are transmitted into behavior and speech without cognitive processing; the symbolic structure collapses. 2) Artistic creativity: Controlled transitions are established between the primary process (imagery) and the secondary process (rational structure); internal material is transformed into symbols that allow for communication and shared meaning. 3)Mystical experience: A descent into similar depths of consciousness occurs, yet the experience is integrated through the heart and value system, allowing it to be expressed with symbols that possess collective and social significance. The rich and multilayered conceptual framework offered by the Ilm al-Nafs perspective provides an opportunity to reconsider the distinctions between psychotic disintegration, artistic creation, and mystical wisdom-consciousness within the context of psycho-spiritual mechanisms. This approach creates a foundation for conceptualizing psychosis—a highly challenging pathology in psychotherapy—from broader dimensions, opening avenues for exploring alternative explanations and potential therapeutic interventions.